What is Molnupiravir, by DRIVE at Emory, Merck and Ridgeback Biotherapeutics Rick Bright and Tam

#Molnupiravir #Merck #RidgebackBiotherapeutics #RickBright #Tamiflu

Welcome to Kimavi Videos (Portrait Mode).

#Molnupiravir #Merck #RidgebackBiotherapeutics #RickBright #Tamiflu

What is Molnupiravir, by DRIVE at Emory, Merck and Ridgeback Biotherapeutics? Rick Bright and Tamiflu?

Molnupiravir is an experimental Covid-19 drug that could be Tamiflu for the Covid 19 pandemic

Only one antiviral has been authorized for use remdesivir from Gilead Sciences Inc., and it provides modest benefit in hospitalized patients

Let's learn more

What is Molnupiravir

Molnupiravir is an experimental antiviral drug which is orally active and was developed for the treatment of influenza

It is a prodrug of the synthetic nucleoside derivative N4-hydroxycytidine, and exerts its antiviral action through introduction of copying errors during viral RNA replication

Activity has also been demonstrated against coronaviruses including SARS, MERS and SARS-CoV-2.

The drug was developed at Emory University by the university's drug innovation company, Drug Innovation Ventures at Emory

It was then acquired by Miami-based company Ridgeback Biotherapeutics, who later partnered with Merck and Co. to develop the drug further

Safety controversy?

In April 2020, a whistleblower complaint by former Head of US Biomedical Advanced Research and Development Authority Rick Bright revealed concerns over providing funding for the further development of molnupiravir due to similar drugs having mutagenic or DNA damaging properties

These claims were denied by George Painter, CEO of DRIVE, noting that toxicity studies on molnupiravir had been carried out

Covid 19 Impact

On December 3rd, 2020, an article was published in the journal Nature on the results of a study on the treatment with molnupiravir of ferrets infected with Covid-19. The study found that the drug was "efficacious" when administered orally to infected ferrets, and that it blocked the transmission of the virus between ferrets after 24 hours following administration of the drug

Who is Rick Bright?

Rick Arthur Bright is an American immunologist, vaccine researcher, public health official, and whistleblower

He was the director of the Biomedical Advanced Research and Development Authority from 2016 to 2020

In May 2020, he filed a whistleblower complaint, alleging that the Trump administration ignored his early warnings about the COVID-19 pandemic and illegally retaliated against him by ousting him from his role and demoting him to a position at the National Institutes of Health

....

....

Thank you from Kimavi, Please visit us at Kimavi.Com for more portrait videos